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Anthropic

  • CEO:DARIO AMODEI
  • HQ:SAN FRANCISCO
  • FUNDING:$60 BIL
  • FOUNDED:2021

Anthropic had a busy February. First Claude Cowork, designed to automate common business processes, spooked the market, sending SaaS, IT and legal services shares $285 billion lower. Then it launched its latest version of Claude Opus, its coding model that’s upending software engineering. Finally, it had a very public feud with the U.S. government. After refusing to budge on safeguards around autonomous weapons and mass domestic surveillance, Anthropic was blacklisted by the Pentagon. But that’s made CEO and cofounder Dario Amodei a hero of sorts in the AI world, with rivals like OpenAI and Google coming to his defense. And business keeps booming. Revenue hit $4.5 billion last year and in February Claude surpassed ChatGPT to become the most downloaded app on the App Store. It’s now valued at $380 billion.

EliseAI

  • CEO:MINNA SONG
  • HQ:NEW YORK
  • FUNDING:$392 MIL
  • FOUNDED:2017

Over 80 percent of the country’s largest property management firms use EliseAI’s chatbots to speed up repetitive admin work like tracking maintenance requests, scheduling apartment tours and renewing leases. CEO Minna Song took a front desk job at a real estate firm to learn about the industry’s pain points before starting the New York-based EliseAI in 2017. At the time, she struggled to convince investors to take a chance on an AI company targeting housing. “Now we go into investor meetings and they’re pitching us back to us,” says Song, 35. In 2023, the startup expanded into another crucial industry: healthcare, where its tech helps verify insurance, make appointments and answer billing questions.

Gamma

  • CEO:GRANT LEE
  • HQ:SAN FRANCISCO
  • FUNDING:$91 MIL
  • FOUNDED:2020

Former investment banker Grant Lee used to waste hours formatting text and designing graphics for PowerPoint presentations. Today, his startup Gamma lets anyone type in a simple text prompt to spin up sleek financial slides, visuals to go with social media posts and even entire websites. The app’s first version, launched in 2020, was a dud: one investor called it “the worst idea” they’d ever heard, Lee, 42, recalls. But the AI craze changed Gamma’s fortunes: It’s been profitable since 2023 and is now valued at $2.1 billion. One hundred million people have used its tools at least once and more than 600,000 are regular users, paying between $9 to $100 a month.

Reflection

  • CEO:MISHA LASKIN
  • HQ:BROOKLYN
  • FUNDING:$2.1 BIL
  • FOUNDED:2024

Chinese AI companies like DeepSeek lead the world on open-source AI models, where the underlying code is visible to clients and can be modified, which has made the Trump administration eager to champion an American alternative. Enter Reflection, a two-year-old Brooklyn-based startup that’s raised $2.1 billion and is valued at $8 billion. Backed by Nvidia, Sequoia, Lightspeed and 1789 Capital, where Donald Trump Jr. is a partner, the company hasn’t publicly released its own AI yet but is spending billions building a data center in South Korea and developing bespoke AIs for Korean companies. Former Google DeepMind researchers Misha Laskin and Ioannis Antonoglou, who led early efforts on Gemini, founded the venture in 2024.

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